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Stereoselective Synthesis
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Stereoselective Synthesis Paperback - 1995

by Robert S. Atkinson


From the publisher

Stereoselective Synthesis Robert S. Atkinson University of Leicester, Leicester. UK Stereoselective Synthesis considers the methods available for the synthesis of simple target molecules, the majority containing not more than two chiral centres, as single stereoisomers. This volume focuses on the factors which give rise to the stereoselectivity and classifies stereoselective reactions accordingly. This classification, and the extensive use of 3-D representations, enables the student to understand the stereochemistry of these reactions and hence apply them to the synthesis of previously unseen target molecules as single stereoisomers. Stereoselective Synthesis presents:

  • a new, unique, simplified classification for stereoselective reactions based on the number of chiral centres created in the product by comparison with the number present in the starting material
  • coverage of the majority of important reaction types used in modern stereoselective synthesis
  • a detailed analysis of factors which bring about asymmetric induction: the interplay between steric and electronic effects, the importance of conformational control and the advantages of intramolecularity in reactions
  • emphasis on synthesis of simple target molecules and on those steps which involve stereochemistry
  • realistic 3-D representations of transition states in which stereoselectivity is created
  • stereochemical vocabulary in accordance with IUPAC rules
Stereoselective Synthesis is an invaluable aid not only to students in understanding this important area but also to those actively engaged in the syntheses of target molecules as single stereoisomers.

From the rear cover

Stereoselective Synthesis considers the methods available for the synthesis of simple target molecules, the majority containing not more than two chiral centres, as single stereoisomers. This volume focuses on the factors which give rise to the stereoselectivity and classifies stereoselective reactions accordingly. This classification, and the extensive use of 3-D representations, enables the student to understand the stereochemistry of these reactions and hence apply them to the synthesis of previously unseen target molecules as single stereoisomers. Stereoselective Synthesis presents:
* a new, unique, simplified classification for stereoselective reactions based on the number of chiral centres created in the product by comparison with the number present in the starting material
* coverage of the majority of important reaction types used in modern stereoselective synthesis
* a detailed analysis of factors which bring about asymmetric induction: the interplay between steric and electronic effects, the importance of conformational control and the advantages of intramolecularity in reactions
* emphasis on synthesis of simple target molecules and on those steps which involve stereochemistry
* realistic 3-D representations of transition states in which stereoselectivity is created
* stereochemical vocabulary in accordance with IUPAC rules
Stereoselective Synthesis is an invaluable aid not only to students in understanding this important area but also to those actively engaged in the syntheses of target molecules as single stereoisomers.

Details

  • Title Stereoselective Synthesis
  • Author Robert S. Atkinson
  • Binding Paperback
  • Edition INTERNATIONAL ED
  • Pages 542
  • Volumes 1
  • Language ENG
  • Publisher Wiley, New York
  • Date 1995-09-11
  • ISBN 9780471954194 / 0471954195
  • Weight 1.91 lbs (0.87 kg)
  • Dimensions 8.95 x 5.97 x 1.38 in (22.73 x 15.16 x 3.51 cm)
  • Library of Congress subjects Organic compounds - Synthesis, Stereochemistry
  • Library of Congress Catalog Number 94020918
  • Dewey Decimal Code 547.2

About the author

Robert S. Atkinson is the author of Stereoselective Synthesis, published by Wiley.

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Stereoselective Synthesis
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Stereoselective Synthesis

by Atkinson, Robert

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