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Advances in Cancer Research, Volume 85
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Advances in Cancer Research, Volume 85 Hardcover - 2002

by Vande Woude, George F. [Editor]; Klein, George [Editor];

  • Used
  • very good
  • Hardcover

Description

Academic Press, 2002-10-14. Hardcover. Very Good. 6x0x9. Ex-Library hardcover in very nice condition with all the usual markings and attachments. Text block clean and unmarked. Tight binding.
Used - Very Good
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First line

Although it is presently not known exactly why loss of the VHL gene results in tumorigenesis, one of the first clues to the function of the VHL protein came with the discovery that clear cell renal carcinoma cells lacking a functional VHL gene misregulate and constitutively express hypoxia-inducible genes like glucose transporter-1 (GLUT1), vascular endothelial growth factor (VEGF), and transforming growth factor (TGF) (Gnarra et al., 1996; Iliopoulos et al., 1996; Siemeister et al., 1996; Knebelmann et al., 1998; de Paulsen et al., 2001).