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Enzyme Systems that Metabolise Drugs and Other Xenobiotics
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Enzyme Systems that Metabolise Drugs and Other Xenobiotics Hardcover - 2001

by Costas Ioannides (Editor)

  • Used

Description

Wiley. Used - Good. Ships from UK in 48 hours or less (usually same day). Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. 100% money back guarantee. We are a world class secondhand bookstore based in Hertfordshire, United Kingdom and specialize in high quality textbooks across an enormous variety of subjects. We aim to provide a vast range of textbooks, rare and collectible books at a great price. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions. We provide a 100% money back guarantee and are dedicated to providing our customers with the highest standards of service in the bookselling industry.
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Details

  • Title Enzyme Systems that Metabolise Drugs and Other Xenobiotics
  • Binding Hardcover
  • Edition First
  • Condition Used - Good
  • Pages 588
  • Volumes 1
  • Language ENG
  • Publisher Wiley
  • Date 2001-12-21
  • Illustrated Yes
  • Features Illustrated, Index, Table of Contents
  • Bookseller's Inventory # Z1-R-001-01680
  • ISBN 9780471894667 / 0471894664
  • Weight 2.1 lbs (0.95 kg)
  • Dimensions 9 x 6 x 1.25 in (22.86 x 15.24 x 3.18 cm)
  • Library of Congress subjects Drugs - Metabolism, Xenobiotics - Metabolism
  • Library of Congress Catalog Number 2001039011
  • Dewey Decimal Code 615.7

From the publisher

In den letzten Jahren haben wir neue Erkenntnisse ber metabolische und toxikologische Aspekte metabolisierender Enzymsysteme gewonnen. Dieser Band gehrt zur Reihe 'Current Toxicology Series' und ist das erste ma gebliche Nachschlagewerk, das sich kritisch mit Enzymsystemen auseinandersetzt, die am Metabolismus von Chemikalien und anderer Xenobiotika beteiligt sind. Ein deutlicher Schwerpunkt liegt dabei auf dem Medikamentenstoffwechsel. Jedes Kapitel behandelt ein spezifisches Enzymsystem und diskutiert detailliert die metabolischen und toxikologischen Aspekte des metabolisierenden Enzymsystems. Das "Handbook of Enzyme Systems for Drugs and other Xenobiotics" ist eine einzigartige Informationsquelle, denn es setzt sich speziell mit dem Thema der Wirkstoff-Forschung und -Entwicklung auseinander. Geschrieben von fhrenden internationalen Experten auf diesem Gebiet.

First line

The meteoric advances in analytical technology that occurred during the last two decades have made possible the analysis of complex mixtures and the determination of chemicals present in minute quantities, thus allowing us to appreciate for the first time the number and diversity of chemicals to which we are exposed, from conception to death.

From the rear cover

This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include:
* enzyme function in the metabolism and bioactivation of xenobiotics

* substrate specificity

* tissue distribution

* species distribution (to include laboratory animals and humans)

* hormonal regulation

* sex differences

* modulation by prior exposure to other chemicals

* age-dependent expression

* pharmacogenetics and modulation by disease.
Enzyme Systems that Metabolise Drugs and Other Xenobiotics will be essential reading for industrial research scientists working in the fine chemicals and pharmaceutical industries, especially those concerned with the safety evaluation of chemicals, and investigating their metabolism, pharmacokinetic characteristics and toxicological properties. The nature and scope of the book will also make it attractive to the research toxicologist and to postgraduate students studying toxicology, as well as to clinicians and pharmacists.

About the author

Costas Ioannides is the author of Enzyme Systems that Metabolise Drugs and Other Xenobiotics, published by Wiley.

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