G-Quadruplex DNA: Methods and Protocols Hard cover - 2009 - 2010th Edition
by Peter Baumann
- New
- Hardcover
Description
Standard delivery: 7 to 12 days
Details
- Title G-Quadruplex DNA: Methods and Protocols
- Author Peter Baumann
- Binding Hard Cover
- Edition number 2010th
- Edition 2010
- Condition New
- Pages 276
- Volumes 1
- Language ENG
- Publisher Humana
- Date 2009-12-18
- Illustrated Yes
- Features Bibliography, Illustrated, Index
- Bookseller's Inventory # ria9781588299505_pod
- ISBN 9781588299505 / 1588299503
- Weight 1.5 lbs (0.68 kg)
- Dimensions 9.8 x 7.2 x 0.9 in (24.89 x 18.29 x 2.29 cm)
- Library of Congress subjects DNA, Telomerase
- Library of Congress Catalog Number 2009933115
- Dewey Decimal Code 572.8
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From the rear cover
Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In G-Quadruplex DNA: Methods and Protocols, experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, G-Quadruplex DNA: Methods and Protocols promises to be a useful resource for those familiar with G-quartets as well as an easy entry point for those researchers from diverse fields who are just developing an interest in the exciting implications of G-quadruplex DNA.
Media reviews
Citations
- Scitech Book News, 06/01/2010, Page 64