Skip to content

Model Organisms In Drug Discovery (Hb 2003)
Stock Photo: Cover May Be Different

Model Organisms In Drug Discovery (Hb 2003) Hardcover - 2003

by Carroll

  • Used
  • very good

Description

Very Good.
Used - Very Good
NZ$249.33
NZ$21.06 Shipping to USA
Standard delivery: 10 to 16 days
More Shipping Options
Ships from indianaabooks (Indiana, United States)
The BIBLIO Guarantee | Ask Seller a Question

Details

  • Title Model Organisms In Drug Discovery (Hb 2003)
  • Author Carroll
  • Binding Hardcover
  • Edition U.S. Edition
  • Condition Used - Very Good
  • Pages 288
  • Volumes 1
  • Language ENG
  • Publisher Wiley, 1
  • Date December 19, 2003
  • Illustrated Yes
  • Features Illustrated, Index, Table of Contents
  • Bookseller's Inventory # 9780470848937
  • ISBN 9780470848937 / 0470848936
  • Weight 1.45 lbs (0.66 kg)
  • Dimensions 9.9 x 6.78 x 0.86 in (25.15 x 17.22 x 2.18 cm)
  • Library of Congress subjects Pharmacogenomics, Drugs - Research
  • Library of Congress Catalog Number 2003013114
  • Dewey Decimal Code 615.19

About indianaabooks Indiana, United States

Biblio member since 2010
Seller rating: This seller has earned a 5 of 5 Stars rating from Biblio customers.

Terms of Sale: 30 day return guarantee, with full refund including shipping costs for up to 30 days after delivery if an item arrives misdescribed or damaged.

Browse books from indianaabooks

From the publisher

Modellorganismen sind sehr hilfreich bei einem systematischen Ansatz zur Klrung einer breiten Palette krankheitsbezogener Fragestellungen.

Aufgrund fortgeschrittener Gentechniken fr Modellorganismen und die Verfgbarkeit ihrer Genomsequenzen, knnen diese Organismen einen gro en Einfluss auf die Wirkstoffentdeckung haben, insbesondere in dem kritischen Bereich der Targetvalidierung krankheitsrelevanter Proteine.

Dieses topaktuelle Buch erlutert die neuesten Fortschritte in den Bereichen Bioinformatik, Proteomik, Genomik sowie Biochemische- und Automationstechnologien, soweit sie sich auf einfache Organismen beziehen, die in der Wirkstoffentdeckung eingesetzt werden.

Fhrende Experten auf diesem Gebiet berichten hier umfassend ber den Bereich der Erforschung von Modellorganismem, die einen gro en Einfluss auf spezifische Therapiebereiche ausgebt hat.

Darber hinaus analysieren sie topaktuelle Anwendungen von Modellsystemen, beschreiben Anwendungen in der Praxis und mgliche Zukunftsperspektiven.

"Model Organisms in Drug Discovery" - eine ntzliche Lektre nicht nur fr Fachleute in der Wirkstoffentdeckung, sondern fr eine Vielzahl von Wissenschaftlern.

First line

A major challenge in the 'post-genomic' world is to rapidly uncover the proteins that may become the high-quality therapeutic targets of the future.

From the rear cover

Fruit flies are "little people with wings" goes the saying in the scientific community, ever since the completion of the Human Genome Project and its revelations about the similarity amongst the genomes of different organisms. It is humbling that most signaling pathways which "define" humans are conserved in Drosophila, the common fruit fly. Feed a fruit fly caffeine and it has trouble falling asleep; feed it antihistamines and it cannot stay awake. A C. elegans worm placed on the antidepressant flouxetine has increased serotonin levels in its tiny brain. Yeast treated with chemotherapeutics stop their cell division. Removal of a single gene from a mouse or zebrafish can cause the animals to develop Alzheimer's disease or heart disease. These organisms are utilized as surrogates to investigate the function and design of complex human biological systems.

Advances in bioinformatics, proteomics, automation technologies and their application to model organism systems now occur on an industrial scale. The integration of model systems into the drug discovery process, the speed of the tools, and the in vivo validation data that these models can provide, will clearly help definition of disease biology and high-quality target validation. Enhanced target selection will lead to the more efficacious and less toxic therapeutic compounds of the future.

This book will be of interest to geneticists, bioinformaticians, pharmacologists, molecular biologists and people working in the pharmaceutical industry, particularly genomics.

About the author

Pamela M. Carroll is the editor of Model Organisms in Drug Discovery, published by Wiley.

Kevin Fitzgerald is the editor of Model Organisms in Drug Discovery, published by Wiley.

Hang on… we’re fetching the requested page.