Preclinical Development Handbook: Toxicology Hardcover - 2008 - 1st Edition
by Shayne Cox Gad (Editor)
- Used
Description
Standard delivery: 5 to 9 days
Details
- Title Preclinical Development Handbook: Toxicology
- Binding Hardcover
- Edition number 1st
- Edition 1
- Condition Used - Very Good
- Pages 1080
- Volumes 1
- Language ENG
- Publisher Wiley-Interscience, U.S.A.
- Date March 14, 2008
- Illustrated Yes
- Features Bibliography, Illustrated, Index, Table of Contents
- Bookseller's Inventory # A07L-00447
- ISBN 9780470248461 / 0470248467
- Weight 3.95 lbs (1.79 kg)
- Dimensions 10 x 7.1 x 1.8 in (25.40 x 18.03 x 4.57 cm)
- Library of Congress subjects Drug Design, Drugs - Toxicology
- Library of Congress Catalog Number 2008003749
- Dewey Decimal Code 615.9
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From the publisher
From the rear cover
Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques.
Each chapter was written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.
Among the key topics covered are:
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In vitro mammalian cytogenetics tests
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Phototoxicity
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Carcinogenicity studies
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The pharmacogenomics of personalized medicine
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Bridging studies
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Toxicogenomics and toxicoproteomics
Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage.
This is a hands-on guide for pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.
