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Vanishing Bone: Conquering a Stealth Disease Caused by Total Hip Replacements
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Vanishing Bone: Conquering a Stealth Disease Caused by Total Hip Replacements Other - 2018 - 1st Edition

by William H. Harris

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Oxford University Press OUP . Other. New.
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Details

  • Title Vanishing Bone: Conquering a Stealth Disease Caused by Total Hip Replacements
  • Binding Other
  • Edition number 1st
  • Edition 1
  • Condition New
  • Pages 248
  • Volumes 1
  • Language ENG
  • Publisher Oxford University Press OUP
  • Date 2018-01-02
  • Features Bibliography, Index
  • Bookseller's Inventory # 6376281009
  • ISBN 9780190687762 / 0190687762
  • Weight 1.05 lbs (0.48 kg)
  • Dimensions 8.3 x 5.8 x 1.1 in (21.08 x 14.73 x 2.79 cm)
  • Library of Congress subjects Total hip replacement, Bone resoption
  • Library of Congress Catalog Number 2017004759
  • Dewey Decimal Code 617.581

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From the publisher

When dozens of holes appeared in a patient's femur alongside his hip prosthesis, experts were baffled as such a phenomenon had never been seen before. Over the first four decades of total hip surgery, the severe bone destruction multiplied, crippling many thousands of patients. Eventually identified as "periprosthetic osteolysis," this devastating disease affected over 1 million patients and was the leading cause of failure in total hip surgery. While total hip surgery dramatically reversed severe arthritis of the hip, the same operation simultaneously created a relentless 'particle generator' in the body. Ironically, in the effort to do good, doctors were simultaneously doing major harm.

Vanishing Bone: Conquering a Stealth Disease Caused by Total Hip Replacements takes readers on a detective adventure in contemporary medical science, from the identification of the cause of the disease through the complex process of affecting its cure. Dr. William H. Harris and his colleagues played an important role in solving the mystery of this disease, pointing to its molecular biology, recognizing the unusual wear of the prostheses, and ultimately developing a new material for use in the manufacture of hip implants. With more than 6 million people walking on this stable, low-wear material, the disease has been virtually eliminated among those with total hip replacements worldwide. Diseases are rarely observed, revealed, and eliminated in one lifetime. Vanishing Bone tells the captivating story of one such disease through an engaging account of scientific and medical innovation.

About the author

William H. Harris, MD, DSc is the Alan Gerry Clinical Professor of Orthopaedic Surgery, Emeritus at Harvard Medical School and Massachusetts General Hospital in Boston, Massachusetts. The Harris Orthopaedic Laboratory at Massachusetts General was founded in 1969 and directed by Dr. Harris until 2004.