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Umpoled Synthons: A Survey of Sources and Uses in Synthesis
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Umpoled Synthons: A Survey of Sources and Uses in Synthesis Hardcover - 1987

by Tapio A. Hase (Editor)


From the publisher

Since the introduction of the concept of synthons in 1967, it has become common among practitioners of organic synthesis to treat numerous synthetic reactions as simple combinations of the appropriate synthons instead of writing out the actual reagents in full. This book provides chemists who plan their synthetic routes manually with information on some of the new umpoled synthons and the use of synthons in planning organic syntheses. The major part of the text is devoted to acyl anions, hydroxycarbonyl and related anions, carbonyl (ALPHA)-cations, and carbonyl (BETA)-anions. Another group discussed comprises carbanionic synthons in which the carbon atom carries a singly bonded heteratom. Emphasis is on the aspects relating to synthetic use. This work includes a tabular presentation of known applications, along with relevant data on the sources, auxiliary reagents, yields, and restrictions. More than 2,000 references cited.

First line

In 1967, E.J. Corey introduced the new concept the new of synthons, defining them as "structural units within a molecule which are related to possible synthetic operations."

Details

  • Title Umpoled Synthons: A Survey of Sources and Uses in Synthesis
  • Author Tapio A. Hase (Editor)
  • Binding Hardcover
  • Edition 1st
  • Pages 416
  • Volumes 1
  • Language ENG
  • Publisher Wiley-Interscience, New York
  • Date 1987-05-11
  • ISBN 9780471806677 / 0471806676
  • Weight 1.57 lbs (0.71 kg)
  • Dimensions 9.58 x 6.36 x 1.09 in (24.33 x 16.15 x 2.77 cm)
  • Library of Congress subjects Organic compounds - Synthesis
  • Library of Congress Catalog Number 86026702
  • Dewey Decimal Code 547.2

About the author

Tapio A. Hase is the author of Umpoled Synthons: A Survey of Sources and Uses in Synthesis, published by Wiley.

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